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Pharmaceutical Sciences Faculty Publications
Within the Past 2 Years

Balthasar, Joseph P. (Professor)

Book Chapters

Book, Chapter in Scholarly Book-New (Published March 2008)

Shin, B. S., Shah, D., Balthasar, J. P. (2008). Pharmacodynamics. In Gad, S. C. (Ed.), Preclinical Development Handbook: ADME and Biopharmaceutical Properties. Hoboken, NJ: John Wiley & Sons, Inc..

Non-Refereed Journal Articles

Journal Article, Academic Journal (Published May 2009)

Shah, D. K., Shin, B. S., Veith, J., Toth, K., Bernacki, R. J., & Balthasar, J. P. (2009). Use of an anti-vascular endothelial growth factor antibody in a pharmacokinetic strategy to increase the efficacy of intraperitoneal chemotherapy.

Journal Article, Academic Journal (Published March 2009)

Shin, B. S., Yoon, C. H., Balthasar, J. P., Choi, B. Y., Hong, S. H., Kim, H. J., Lee, J. B., Hwang, S. W., & Yoo, S. D. (2009). Prediction of drug bioavailability in humans using immobilized artificial membrane phosphatidylcholine column chromatography and in vitro hepatic metabolic clearance.

Journal Article, Academic Journal (Published February 2009)

Urva, S. R., Shin, B. S., Yang, V. C., & Balthasar, J. P. (2009). Sensitive high performance liquid chromatographic assay for assessment of doxorubicin pharmacokinetics in mouse plasma and tissues.

Journal Article, Academic Journal (Published November 2008)

Wang, W., Wang, E. Q., & Balthasar, J. P. (2008). Monoclonal antibody pharmacokinetics and pharmacodynamics.

Journal Article, Academic Journal (Accepted May 2009)

Urva, S. R., Yang, V. C., & Balthasar, J. P. (2009). Development and validation of an enzyme linked immunosobent assay for the quantification of carcinoembryonic antigen in mouse plasma.

Journal Article, Academic Journal (Accepted May 2009)

Urva, S. R., Yang, V. C., & Balthasar, J. P. (2009). Physiologically based pharmacokinetic model for T84.66, a monoclonal anti-CEA antibody.

Journal Article, Academic Journal (Submitted May 2009)

Urva, S. R., Yang, V. C., & Balthasar, J. P. (2009). An ELISA for quantification of T84.66, a monoclonal anti-CEA antibody, in mouse plasma.

Balu-Iyer, Sathy V. (Associate Professor)

Refereed Journal Articles

Journal Article, Academic Journal (Published May 2009)

Kosloski, M., Miclea, R. D., & Balu-Iyer, S. V. (2009). Role of Glycosylation in Conformational stability, activity, macromolecular interaction and immunogenicity of recombinant human Factor VIII. AAPS Journal, In Press.

Journal Article, Academic Journal (Published September 2008)

Ramani, K., Miclea, R. D., Gaitonde, P., Straubinger, R. M., Balu-Iyer, S. V. (2008). Passive Transfer of Polyethyleneglycol to Liposomal-Recombinant Human FVIII Enhances its Efficacy in a Murine Model for Hemophilia A. Journal of Pharmaceutical Sciences, 97(9), 3753-3764.

Journal Article, Academic Journal (Published July (3rd Quarter/Summer) 2008)

Themistou, E., Singh, I., Balu-Iyer, S. V., Alexandridis, P., & Neelamegham, S. (2008). Change in Solution Structure of Human Blood Protein von Willebrand Factor Caused by Shear. Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.), 49(2), 399-400.

Journal Article, Academic Journal (Published April (2nd Quarter/Spring) 2008)

Ramani, K., Miclea, R. D., Purohit, V. S., Straubinger, R. M., Mager, D. E., & Balu-Iyer, S. V. (2008). Phosphatidylserine Containing Liposomes reduce Immunogenicity of Recombinant Human Factor VIII in a Murine Model of Hemophilia A. Journal. Pharmaceutical Sciences, 97, 1386-1397.

Journal Article, Academic Journal (Accepted March 2009)

Peng, A., Gaitonde, P., Kosloski, M. P., Miclea, R. D., Varma, P., & Balu-Iyer, S. V. (2009). Effect of route of administration of human recombinant Factor VIII on its immunogenicity in Hemophilia A mice. Journal. Pharmaceutical Sciences, In press.

Journal Article, Academic Journal (Accepted March 2009)

Simpson-Abelson, M. R., Purohit, V. S., Pang, W. M., Iyer, V., Odunsi, K., Demmy, T., Yakota, S. J., Loyall, J. L., Kelleher, R. J., Balu-Iyer, S. V., & Bankert, R. B. (2009). IL-12 Delivered Intratumorally by Multilamellar Liposomes Reactivates Memory T Cells in Human Tumor Microenvironments. Clin. Immunology, In press.

Journal Article, Academic Journal (Revising to Resubmit May 19, 2009)

Themistou, E., Singh, I., Shang, C., Balu-Iyer, S. V., Alexandridis, P., & Neelamegham, S. (2009). Application of fluorescence spectroscopy to quantify shear-induced protein conformation change. Biophysical Journal.

Non-Refereed Journal Articles

Journal Article, Academic Journal (Published September 2008)

Korotchkina, L. G., Ramani, K., & Balu-Iyer, S. V. (2008). Folding consideration of therapeutic proteins. Prog Mol Biol Transi Sci, 83, 255-270.

Blanco, Javier G. G. (Assistant Professor)

Refereed Journal Articles

Journal Article, Academic Journal (Published September 2009)

Choi, J. Y., Barlow, W. E., Hong, C. C., Blanco, J. G., Davis, W., Rae, J. M., Yeh, I. T., Hutchins, L. F., Livingston, R., Martino, S., Lyss, A. P., Osborne, K., Abeloff, M., Hayes, D. F., & Ambrosone, C. B. (2009). Nitric oxide synthase (NOS3) variants and disease-free survival among treated and untreated breast cancer patients in a SWOG Clinical Trial (S8897). Clinical Cancer Research, NA(NA), NA.

Journal Article, Academic Journal (Published February 2009)

Gonzalez-Covarrubias, V. M., Zhang, J., Kalabus, J. L., Relling, M. V., & Blanco, J. G. (2009). Pharmacogenetics of human carbonyl reductase 1 (CBR1) in livers from black and white donors. Drug Metabolism and Disposition, 37(2), 400-407.

Journal Article, Academic Journal (Published July (3rd Quarter/Summer) 2008)

Blanco, J. G., Leisenring, W. M., Kawashima, T. I., Davies, S. M., Relling, M. V., Robison, L. L., Sklar, C. A., Stovall, M., & Bhatia, S. (2008). Genetic polymorphisms in the carbonyl reductase 3 gene CBR3 and the NAD(P)H:quinone oxidoreductase 1 gene NQO1 in patients who developed anthracycline-related congestive heart failure after childhood cancer.. Cancer, 112(12), 2789-2795.

Journal Article, Academic Journal (Published July (3rd Quarter/Summer) 2008)

Gonzalez-Covarrubias, V., Kalabus, J. L., & Blanco, J. G. (2008). Inhibition of polymorphic human carbonyl reductase 1 (CBR1) by the cardioprotectant flavonoid 7-monohydroxyethyl rutoside (monoHER). Pharm Res, 25(7), 1730-1734.

Journal Article, Academic Journal (Accepted September 2009)

Zhang, J., & Blanco, J. G. (2009). Identification of the promoter of human carbonyl reductase 3 (CBR3) and impact of common promoter polymorphisms on hepatic CBR3 mRNA expression. To appear in Pharmaceutical Research, NA(NA), NA.

Conference Proceedings

Conference Proceeding (Accepted September 30, 2009)

C, S. L., Blanco, J. G., W, L., D, E., D, V., C, H., M, R. V., & S, B. (2009). Anthracycline related cardiomiopaty (AC) in childhood cancer survivors: dose-specific role of genetic polymorphisms in CBR3. European Symposium on Late Complications after Childhood Cancer 2009 (ESLCCC09).

Conference Proceeding (Accepted September 30, 2009)

Kalabus, J. L., Jamil, R. G., & Blanco, J. G. (2009). Assessment of CBR1 Expression in Heart Samples from Donors with Down Syndrome. American Association of Pharmaceutical Scientists.

Other Intellectual Contributions

Abstract (Published November 2008)

Gonzalez-Covarrubias, V. M., & Blanco, J. G. (2008). Pharmacogenetics of human carbonyl reductase 1 (CBR1) in livers from black and white donors.

Brazeau, Daniel A. (Research Associate Professor)

Refereed Journal Articles

Journal Article, Academic Journal (Published March 2009)

Telang, U., Brazeau, D. A., & Morris, M. E. (2009). Comparison of the effects of phenethyl isothiocyanate and sulforaphane on gene expression in breast cancer and normal mammary epithelial cells.. Exp Biol Med, 234(3), 287-295.

Journal Article, Academic Journal (Published February 2, 2009)

Brazeau, D. A., Brazeau, G. A. (2009). Role of the Genomics Revolution in Pharmaceutics. Laboratory Medicine, 40(5), 261-266.

Journal Article, Academic Journal (Published October (4th Quarter/Autumn) 2008)

Brazeau, D. A., Brazeau, G. A. (2008). Pharmacogenomics of Warfarin Therapy for venous thromboembolism.. Clinical Laboratory(CL-8), 2-5.

Journal Article, Academic Journal (Published September 9, 2008)

Chanda, P., Sucheston, L. E., Zhang, A., Brazeau, D. A., Freudenheim, J. L., Ambrosone, C., & Ramanathan, M. (2008). AMBIENCE: A Novel Approach and Efficient Algorithm for Identifying Informative Genetic and Environment Interactions Associated with Complex Phenotypes. Genetics.

Non-Refereed Journal Articles

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2009)

Renzi, S. E., Sauberan, M. E., Brazeau, D. A., & Brazeau, G. A. (2009). Leadership Activities among Students with Varying Pre-Pharmacy Years in College. American Journal of Pharmaceutical Education, 72(6), Article 149.

Journal Article, Academic Journal (Accepted June 2008)

Atchison, A. D., Sammarco, P. W., & Brazeau, D. A. (2008). Genetic Connectivity in Corals on the Flower Garden Banks, Gulf of Mexico, and Surrounding Oil/Gas Platforms. Experimental Marine Biology and Ecology, 365(1), 1-12.

Journal Article, Academic Journal (Revising to Resubmit July (3rd Quarter/Summer) 2009)

Tornatore-Morse, K. M., Brazeau, D. A., Dole, K., Gillis, K. A., Wilding, G. E., Leca, N., Yassa, S., & Venuto, R. C. (2009). The Influence of Race and Gender on Time-Dependent Expression of MDR-1 in Stable Renal Transplant Recipients.. Journal of Pharmacogenomics.

Journal Article, Academic Journal (In Preparation; Not Yet Submitted May 15, 2009)

Hsieh, T. K., Brazeau, D. A., & Coffroth, M. (2009). Cryptic symbiont types revealed in Caribbean octocorals after experimental and natural bleaching.

Journal Article, Academic Journal (Working Paper September 2009)

Tornatore-Morse, K. M., Brazeau, D. A., Danison, R., Wilding, G. E., Dole, K., & Venuto, R. C. (2009). MDR1 Expression and Cyclosporine Pharmacokinetics in African American and Caucasian Renal Transplant Recipients.. Clin. Pharmacol. Therapeutics.

Journal Article, Academic Journal (Working Paper August 2009)

Ma, Q., Venuto, C. S., Brazeau, D. A., Zingman, B. S., Reichman, R. C., Forrest, A., & Morse, E. D. (2009). Effects of CYP2B6 single nucleotide polymorphisms and substance abuse on efavirenz pharmacokinetics. Clin Pharmacol Ther.

Journal Article, Academic Journal (Working Paper August 2009)

Ma, Q., Acheampong, F. A., Brazeau, D. A., Zingman, B. S., Forrest, A., & Morse, E. D. (2009). Relationship between CYP3A5 Single Nucleotide Polymorphisms (SNPs) and Protease Inhibitor (PI) Trough Concentrations in HIV+ Patients during Therapeutic Drug Monitoring. Ther Drug Monit.

Other Intellectual Contributions

Abstract (Published April (2nd Quarter/Spring) 2009)

Jaenecke, K., Stewart, M., Morris, M. E., Brazeau, D. A., & Havard, P. F. (2009). A Semi-Quantitative Comparison of P-glycoprotein Protein Expression in Peripheral Blood Mononuclear Cells Between the Maternal and Fetal Compartments. Accepted to the 2009 APhA Annual Meeting, San Antonio TX, April 3rd - 6th, 2009.. San Antonio TX: 2009 APhA Annual Meeting, San Antonio TX, April 3rd - 6th, 2009..

Abstract (Published March 21, 2009)

Tornatore-Morse, K. M., Suchada, P., Brazeau, D. A., & Venuto, R. C. (2009). Time Dependent Expression of MRP-2 in Periperhal Mononuclear Cells in African American and Caucasian Renal Transplant Recipients (ed., vol. 85, pp. S74). New York, New York: Clin. Pharmacol.Ther.

Abstract (Published February 2009)

Lubin, R., Tam, P. Y., Brazeau, D. A., Forrest, A., Colombo, D., Liu, Z., & Havard, P. F. (2009). The Relationship of ABCB1 Gene Expression and the C3435T and G2677T Polymorphisms between Maternal and Fetal Peripheral Blood Mononuclear Cells (PBMCs) [Abstract 931]. Montreal: 2009 16th Conference Retrovirus Opporunistic Inefections Meeting.

Abstract (Published February 2009)

Tornatore-Morse, K. M., Suchada, P., Brazeau, D. A., & Venuto, R. C. (2009). Time Dependent Expression of MRP-2 in Periperhal Mononuclear Cells in African American and Caucasian Renal Transplant Recipients (vol. 85). Clin Pharmacol Ther.

Abstract (Published January (1st Quarter/Winter) 2008)

Suchada, P., Brazeau, D. A., Dole, K., Venuto, R. C., & Tornatore-Morse, K. M. (2008). Quantitative real-time PCR Analysis of MRP-2 Expression in Peripheral Mononuclear Cells (3rd ed., vol. 82). Clin Pharmacol Ther.

DuBois, Debra C. (Research Associate Professor)

Books

Book, Textbook-New (Published September 2008)

Almon, R. R., Dubois, D. C., & Almon, A. S. (2008). Humans: How They function. New York: Pearson.

Refereed Journal Articles

Journal Article, Academic Journal (Published March 2009)

Almon, R. R., Dubois, D. C., Lai, W., Xue, B., Nie, J., & Jusko, W. J. (2009). Gene expression analysis of hepatic roles in cause and development of diabetes in Goto-Kakizaki rats.. J Endocrinol, 200, 331-346.

Journal Article, Academic Journal (Published February 2009)

Landersdorfer, C. B., Dubois, D. C., Almon, R. R., & Jusko, W. J. (2009). Mechanism-based modeling of nutritional and leptin influences on growth in normal and type 2 diabetic rats.. J Pharmacol Exp Ther, 328, 644-651.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2009)

Earp, J. C., Dubois, D. C., Almon, R. R., & Jusko, W. J. (2009). Quantitative dynamic models of arthritis progression in the rat.. Pharm Res, 26, 196-203.

Journal Article, Academic Journal (Published October (4th Quarter/Autumn) 2008)

Yao, Z., Dubois, D. C., Almon, R. R., & Jusko, W. J. (2008). Pharmacodynamic/Pharmacogenomic Modeling of Insulin Resistance Genes in Rat Muscle After Methylprednisolone Treatment: Exploring Regulatory Signaling Cascades. Gene Reg. Sys. Biol., 2, 141-161.

Journal Article, Academic Journal (Published October (4th Quarter/Autumn) 2008)

Almon, R. R., Yang, E., Lai, W., Androulakis, I. P., Ghimbovschi, S., Hoffman, E. P., Jusko, W. J., & Dubois, D. C. (2008). Relationships between circadian rhythms and modulation of gene expression by glucocorticoids in skeletal muscle.. Am J Physiol Regul Integr Comp Physiol., 295, R1031-R1047.

Journal Article, Academic Journal (Published September 2008)

Almon, R. R., Yang, E., Lai, W., Androulakis, I. P., Dubois, D. C., & Jusko, W. J. (2008). Circadian variations in rat liver gene expression: relationships to drug actions.. J Pharmacol Exp Ther, 326, 700-716.

Journal Article, Academic Journal (Published August 2008)

Earp, J. C., Dubois, D. C., Molan, D. S., Pyszcznski, N. A., Keller, C. E., Almon, R. R., & Jusko, W. J. (2008). Modeling corticosteroid effects in a rat model of rheumatoid arthritis I: mechanistic disease progression model for the time course of collagen-induced arthritis in Lewis rats. J. Pharmacol. Exp. Ther., 326, 532-545.

Journal Article, Academic Journal (Published August 2008)

Earp, J. C., Dubois, D. C., Molano, D. S., Pyszczynski, N. A., Almon, R. R., & Jusko, W. J. (2008). Modeling corticosteroid effects in a rat model of rheumatoid arthritis II: mechanistic pharmacodynamic model for dexamethasone effects in Lewis rats with collagen-induced arthritis.. J Pharmacol Exp Ther., 326, 546-554.

Non-Refereed Journal Articles

Journal Article, Academic Journal (Published April (2nd Quarter/Spring) 2008)

Hazra, A., Pyszczynski, N. A., Dubois, D. C., Almon, R. R., & Jusko, W. J. (2008). Modeling of corticosteroid effects on hepatic low-density lipoprotein receptors and plasma lipid dynamics in rats. Pharm Res, 25(4), 769-780.

Journal Article, Academic Journal (Published February 14, 2008)

Hazra, A., Dubois, D. C., Almon, R. R., Snyder, G. S., & Jusko, W. J. (2008). Pharmacodynamic Modeling of Acute and Chronic Effects of Methylprednisolone on Hepatic Urea Cycle Genes in Rats. Gene Regulation and Systems Biology, 2, 1-19.

Other Intellectual Contributions

Comparative Study (Published March 2008)

Yang, E., Almon, R. R., Dubois, D. C., Androulakis, I. P., & Jusko, W. J. (2008). Extracting global system dynamics of corticosteroid genomic effects in rat liver (3rd ed., vol. 324, pp. 1243-1254). J Pharmacol Exp Ther.

Fung, Ho Leung (Professor)

Refereed Journal Articles

Journal Article, Academic Journal (Published May 21, 2009)

Pei-Suen, T., Vamsi, A., & Fung, H. (2009). Dissociation between superoxide accumulation and nitroglycerin-induced tolerance.. J Pharmacol Exp Ther, 327(1), 97-104.

Journal Article, Academic Journal (Published May 21, 2009)

Fung, H., Tsou, P., Bullita, J. B., Tran, D. C., Page, N. A., Soda, D., & Fung, S. (2009). Pharmacokinetics of 1,4-butanediol in rats: bioactivation to gamma-hydroxybutyric. AAPS J, 10(1), 56-69.

Journal Article, Academic Journal (Published May 21, 2009)

Tsou, P., Addanki, V., Haas, J. A., Page, N. A., & Fung, H. (2009). Role of glutaredoxin-mediated protein S-glutathionylation in cellular nitroglycerin tolerance. Journal of Pharmacology and Experimental Therapeutics, 329(2), 649-56.

Gao, Wenqing (Assistant Professor)

Book Chapters

Book, Chapter in Scholarly Book-New (Accepted May 2009)

Dalton, J. T., Gao, W. (2009). Androgen Receptor: Chemistry and structural biology of androgen receptor, and its role and potential as a target in disease. In Nuclear Receptors. Springer.

Refereed Journal Articles

Journal Article, Academic Journal (Published September 30, 2009)

Pan, Y., Gao, W., & Yu, A. (2009). MicroRNAs regulate CYP3A4 expression via direct and indirect targeting. Drug Metab Dispos, 37(10), 2112-2117.

Journal Article, Professional Journal (Accepted March 2009)

Gao, W. (2009). Peptide Antagonist of the Androgen Receptor. To appear in Current Pharmaceutical Design.

Non-Refereed Journal Articles

Journal Article, Professional Journal (Submitted June 2009)

Kennedy, B. A., Gao, W., Huang, T., & Jin, V. X. (2009). HRTBLDb: an informative data resource for Hormone Receptors Target Binding Loci.

Jusko, William J. (SUNY Distinguished Professor)

Refereed Journal Articles

Journal Article, Academic Journal (Published March 2009)

Almon, R. R., Dubois, D. C., Lai, W., Xue, B., Nie, J., & Jusko, W. J. (2009). Gene expression analysis of hepatic roles in cause and development of diabetes in Goto-Kakizaki rats.. J Endocrinol, 200, 331-346.

Journal Article, Academic Journal (Published February 2009)

Landersdorfer, C. B., Dubois, D. C., Almon, R. R., & Jusko, W. J. (2009). Mechanism-based modeling of nutritional and leptin influences on growth in normal and type 2 diabetic rats.. J Pharmacol Exp Ther, 328, 644-651.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2009)

Bulitta, J. B., Ly, N. S., Yang, J. C., Forrest, A., Jusko, W. J., & Tsuji, B. T. (2009). Development and Qualification of a Pharmacodynamic Model for the Pronounced Inoculum Effect of Ceftazidime against Pseudomonas aeruginosa. Antimicrob. Ag. Chemother., 53(1), 46-56.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2009)

Jin, J. Y. (2009). Pharmacodynamics of Glucose Regulation by Methylprednisolone. I. Adrenalectomized Rats. Biopharm. Drug Disp., 30, 21-34.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2009)

Earp, J. C., Dubois, D. C., Almon, R. R., & Jusko, W. J. (2009). Quantitative dynamic models of arthritis progression in the rat.. Pharm Res, 26, 196-203.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2009)

Mager, D. E., Woo, S., & Jusko, W. J. (2009). Scaling Pharmacodynamics from In Vitro and Preclinical Animal Studies to Humans. Drug Metab. Pharmacokin., 24(1), 16-24.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 20, 2009)

Jin, J. Y., & Jusko, W. J. (2009). Pharmacodynamics of Glucose Regulation by Methylprednisolone. Biopharm. Drug Disp., 30, 35-48.

Journal Article, Academic Journal (Published October (4th Quarter/Autumn) 2008)

Rohatagi, S., Carrothers, T. J., Jin, J. Y., Jusko, W. J., Khariton, T., Walker, J., Truitt, K., & Salazar, D. E. (2008). Model-Based Development of a PPARγ Agonist, Rivoglitazone, to Aid Dose Selection and Optimize Clinical Trial Designs. J. Clin. Pharmacol., 48, 1420-1429.

Journal Article, Academic Journal (Published October (4th Quarter/Autumn) 2008)

Yao, Z., Dubois, D. C., Almon, R. R., & Jusko, W. J. (2008). Pharmacodynamic/Pharmacogenomic Modeling of Insulin Resistance Genes in Rat Muscle After Methylprednisolone Treatment: Exploring Regulatory Signaling Cascades. Gene Reg. Sys. Biol., 2, 141-161.

Journal Article, Academic Journal (Published October (4th Quarter/Autumn) 2008)

Almon, R. R., Yang, E., Lai, W., Androulakis, I. P., Ghimbovschi, S., Hoffman, E. P., Jusko, W. J., & Dubois, D. C. (2008). Relationships between circadian rhythms and modulation of gene expression by glucocorticoids in skeletal muscle.. Am J Physiol Regul Integr Comp Physiol., 295, R1031-R1047.

Journal Article, Academic Journal (Published September 2008)

Almon, R. R., Yang, E., Lai, W., Androulakis, I. P., Dubois, D. C., & Jusko, W. J. (2008). Circadian variations in rat liver gene expression: relationships to drug actions.. J Pharmacol Exp Ther, 326, 700-716.

Journal Article, Academic Journal (Published August 2008)

Earp, J. C., Dubois, D. C., Molan, D. S., Pyszcznski, N. A., Keller, C. E., Almon, R. R., & Jusko, W. J. (2008). Modeling corticosteroid effects in a rat model of rheumatoid arthritis I: mechanistic disease progression model for the time course of collagen-induced arthritis in Lewis rats. J. Pharmacol. Exp. Ther., 326, 532-545.

Journal Article, Academic Journal (Published August 2008)

Earp, J. C., Dubois, D. C., Molano, D. S., Pyszczynski, N. A., Almon, R. R., & Jusko, W. J. (2008). Modeling corticosteroid effects in a rat model of rheumatoid arthritis II: mechanistic pharmacodynamic model for dexamethasone effects in Lewis rats with collagen-induced arthritis.. J Pharmacol Exp Ther., 326, 546-554.

Journal Article, Academic Journal (Published July (3rd Quarter/Summer) 2008)

Earp, J. C., Pyszczynski, N. A., Molano, D. S., & Jusko, W. J. (2008). Pharmacokinetics of Dexamethasone in a Rat Model of Rheumatoid Arthritis. Biopharm. Drug Disp., 29, 366-372.

Journal Article, Academic Journal (Published June 2008)

Mager, D. E., & Jusko, W. J. (2008). Development of Translational Pharmacokinetic–Pharmacodynamic Models. Clin. Pharmacol. Ther., 83(6), 909-912.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2008)

Woo, S., Krzyzanski, W., & Jusko, W. J. (2008). Pharmacodynamic model for chemotherapy-induced anemia in rats. Cancer Chem. Pharmacol., 62, 123-133.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2008)

Woo, S., Krzyzanski, W., Duliege, A., Stead, R. R., & Jusko, W. J. (2008). Population Pharmacokinetics and Pharmacodynamics of Peptidic Erythropoiesis Receptor Agonist (ERA) in Healthy Volunteers. J. Clin. Pharmacol., 48, 43-52.

Non-Refereed Journal Articles

Journal Article, Academic Journal (Published April (2nd Quarter/Spring) 2008)

Hazra, A., Pyszczynski, N. A., Dubois, D. C., Almon, R. R., & Jusko, W. J. (2008). Modeling of corticosteroid effects on hepatic low-density lipoprotein receptors and plasma lipid dynamics in rats. Pharm Res, 25(4), 769-780.

Journal Article, Academic Journal (Published February 14, 2008)

Hazra, A., Dubois, D. C., Almon, R. R., Snyder, G. S., & Jusko, W. J. (2008). Pharmacodynamic Modeling of Acute and Chronic Effects of Methylprednisolone on Hepatic Urea Cycle Genes in Rats. Gene Regulation and Systems Biology, 2, 1-19.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2008)

Landersdorfer, C. B., & Jusko, W. J. (2008). Pharmacokinetic/pharmacodynamic modelling in diabetes mellitus. Clin Pharmacokinet, 47(7), 417-448.

Other Intellectual Contributions

Comparative Study (Published March 2008)

Yang, E., Almon, R. R., Dubois, D. C., Androulakis, I. P., & Jusko, W. J. (2008). Extracting global system dynamics of corticosteroid genomic effects in rat liver (3rd ed., vol. 324, pp. 1243-1254). J Pharmacol Exp Ther.

Krzyzanski, Wojciech (Assistant Professor)

Refereed Journal Articles

Journal Article, Academic Journal (Published May 2009)

Marathe, A., Krzyzanski, W., & Mager, D. E. (2009). Numerical Validation and Properties of a Rapid Binding Approximation of a Target-Mediated Drug Disposition Pharmacokinetic Model. J Pharmacokinet Pharmacodyn, 36, 199-219.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2008)

Woo, S., Krzyzanski, W., & Jusko, W. J. (2008). Pharmacodynamic model for chemotherapy-induced anemia in rats. Cancer Chem. Pharmacol., 62, 123-133.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2008)

Woo, S., Krzyzanski, W., Duliege, A., Stead, R. R., & Jusko, W. J. (2008). Population Pharmacokinetics and Pharmacodynamics of Peptidic Erythropoiesis Receptor Agonist (ERA) in Healthy Volunteers. J. Clin. Pharmacol., 48, 43-52.

Non-Refereed Journal Articles

Journal Article, Professional Journal (Published June 2008)

Krzyzanski, W., Perez-Ruixo, J. J., & Vermeulen, A. (2008). Basic pharamacodynamic models for agents that alter the lifespan distribution of natural cells. Journal of Pharmacokinetics and Pharmacodynamics, 35, 349-377.

Journal Article, Academic Journal (Published June 2008)

Wyska, E., & Krzyzanski, W. (2008). Pharmacokinetics and pharmacodynamics of erythropoietin receptor in healthy volunteers. Naunyn Schmiedebergs Arch Pharmacol, 377(4-6), 637-645.

Journal Article, Academic Journal (Published February 2008)

Wiczling, P., & Krzyzanski, W. (2008). Flow cytometric assessment of homeostatic aging of reticulocytes in rats. Exp Hematol, 36(2), 119-127.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2008)

Pérez-Ruixo, J. J., Hing, J., & Krzyzanski, W. (2008). Pharmacodynamic analysis of recombinant human erythropoietin effect on reticulocyte production rate and age distribution in healthy subjects. Clin Pharmacokinet, 47(6), 399-415.

Mager, Donald E. (Assistant Professor)

Refereed Journal Articles

Journal Article, Academic Journal (Published June 2009)

Abraham, A. K., Ramanathan, M., Weinstock-Guttman, B., & Mager, D. E. (2009). Mechanisms of interferon-beta effects on bone homeostasis. Biochem Pharmacol, 77, 1757-1762.

Journal Article, Academic Journal (Published May 2009)

Marathe, A., Krzyzanski, W., & Mager, D. E. (2009). Numerical Validation and Properties of a Rapid Binding Approximation of a Target-Mediated Drug Disposition Pharmacokinetic Model. J Pharmacokinet Pharmacodyn, 36, 199-219.

Journal Article, Academic Journal (Published April (2nd Quarter/Spring) 2009)

Abraham, A. K., Mager, D. E., Gao, X., Li, M., Healy, D. R., & Maurer, T. S. (2009). Mechanism-based pharmacokinetic/pharmacodynamic model of parathyroid hormone-calcium homeostasis in rats and humans. J Pharmacol Exp Ther, 330, 169-178.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2009)

Mager, D. E., Woo, S., & Jusko, W. J. (2009). Scaling Pharmacodynamics from In Vitro and Preclinical Animal Studies to Humans. Drug Metab. Pharmacokin., 24(1), 16-24.

Journal Article, Academic Journal (Published August 2008)

Marathe, A., Peterson, M. C., & Mager, D. E. (2008). Integrated cellular bone homeostasis model for denosumab pharmacodynamics in multiple myeloma patients. J Pharmacol Exp Ther, 326, 555-562.

Journal Article, Academic Journal (Published July (3rd Quarter/Summer) 2008)

Hong, Y., Dingemanse, J., & Mager, D. E. (2008). Pharmacokinetic/pharmacodynamic modeling of renin biomarkers in subjects treated with the renin inhibitor aliskiren. Clin Pharmacol Ther, 84(1), 136-143.

Journal Article, Academic Journal (Published June 2008)

Mager, D. E., & Jusko, W. J. (2008). Development of Translational Pharmacokinetic–Pharmacodynamic Models. Clin. Pharmacol. Ther., 83(6), 909-912.

Journal Article, Academic Journal (Published June 2008)

Hong, Y., Rohatagi, S., Habtemariam, B., Walker, J. R., Schwartz, S. L., & Mager, D. E. (2008). Population exposure-response modeling of metformin in patients with type 2 diabetes mellitus. J Clin Pharmacol, 48(6), 696-707.

Journal Article, Academic Journal (Published April (2nd Quarter/Spring) 2008)

Ramani, K., Miclea, R. D., Purohit, V. S., Straubinger, R. M., Mager, D. E., & Balu-Iyer, S. V. (2008). Phosphatidylserine Containing Liposomes reduce Immunogenicity of Recombinant Human Factor VIII in a Murine Model of Hemophilia A. Journal. Pharmaceutical Sciences, 97, 1386-1397.

Journal Article, Academic Journal (Published March 2008)

Cao, Y. J., Mager, D. E., Simonsick, E. M., Hilmer, S. N., Ling, S. M., Windham, B. G., Crentsil, V., Yasar, S., Fried, L. P., & Abernethy, D. R. (2008). Physical and Cognitive Performance and Burden of Anticholinergics, Sedatives, and ACE Inhibitors in Older Women. Clin Pharmacol Ther, 83(3), 422-429.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2008)

Gengo, F. M., Rubin, L., Robson, M., Rainka, M., Mager, D. E., & Bates, V. (2008). Effects of Ibuprofen on the Magnitude and Duration of Aspirin‘s Inhibition of Platelet Aggregation: Clinical Consequences in Stroke Prophylaxis. J Clin Pharmacol, 48(1), 117-122.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2008)

Hong, Y., Gengo, F. M., Rainka, M. N., Bates, V. E., & Mager, D. E. (2008). Population pharmacodynamic modelling of aspirin- and Ibuprofen-induced inhibition of platelet aggregation in healthy subjects. Clin Pharmacokinet, 47(2), 129-137.

Journal Article, Academic Journal (Accepted June 2009)

Xu, C., Barchet, T. M., & Mager, D. E. (2009). Quantitative structure-property relationships of camptothecins in humans. Cancer Chemother Pharmacol.

Other Intellectual Contributions

Magazine/Trade Publication (Published December 2008)

Al-share, Q. Y., Cirincione, B., & Mager, D. E. (2008). A focus on type 2 diabetes mellitus (vol. 11, pp. 18-24). AAPS Newsmagazine.

Morris, Marilyn E. (Professor)

Book Chapters

Book, Chapter in Scholarly Book-New (Submitted March 2009)

An, G., Morris, M. E. (2009). Herbal Supplement-based Interactions. In Pang, K. S., Rodrigues, A. D., Peter, R. (Eds.), Enzymatic- and Transporter-Based Drug Drug Interactions: Progress and Future Challenges. Springer.

Book, Chapter in Scholarly Book-New (Submitted May 2008)

Morris, M. E., Gandhi, Y. A. (2008). ABC Transporters in Intestinal and Hepatic Efflux. In Hu, M., Li, X. (Eds.), Oral Bioavailability: Basic Principles, Advance Concepts and Applications,. Wiley.

Refereed Journal Articles

Journal Article, Academic Journal (Published June 2009)

Zhang, S., Sagawa, K., Arnold, R. D., Tseng, E., Wang, X., & Morris, M. E. (2009). Interactions between the flavonoid biochanin A and P-glycoprotein substrates in rats: In vitro and in vivo. J Pharm Sci, e-pub.

Journal Article, Academic Journal (Published May 2009)

Pan, Y., Morris, M. E., & Yu, A. (2009). MicroRNA-328 Negatively Regulates the Expression of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Cancer Cells. Mol Pharmacol, 75(6), 1374-1379.

Journal Article, Academic Journal (Published April (2nd Quarter/Spring) 2009)

Cui, D., & Morris, M. E. (2009). The Drug of Abuse {gamma}-Hydroxybutyrate is a Substrate for SMCT1 (SLC5A8): Characterization of SMCT-mediated Uptake and Inhibition.. Drug Metab Disp, e-pub.

Journal Article, Academic Journal (Published March 2009)

Telang, U., Brazeau, D. A., & Morris, M. E. (2009). Comparison of the effects of phenethyl isothiocyanate and sulforaphane on gene expression in breast cancer and normal mammary epithelial cells.. Exp Biol Med, 234(3), 287-295.

Journal Article, Academic Journal (Published November 2008)

Wang, Q., Wang, X., & Morris, M. E. (2008). Effects of L-lactate and D-mannitol on gamma-hydroxybutyrate toxicokinetics and toxicodynamics in rats.. Drug Metab Disp, 36(11), 2244-2251.

Journal Article, Academic Journal (Published October (4th Quarter/Autumn) 2008)

Pang, K. S., Morris, M. E., & Sun, H. (2008). Formed and preformed metabolites: facts and comparisons.. J Pharm Pharmacol, 60(10), 1247-1275.

Non-Refereed Journal Articles

Journal Article, Academic Journal (Published October (4th Quarter/Autumn) 2008)

Wang, X., & Morris, M. E. (2008). Pharmacokinetics and bioavailability of the flavonoid 7,8-benzoflavone in rats. J Pharm Sci., 97(10), 4546-4556.

Journal Article, Academic Journal (Published September 2008)

Moon, Y. J., Shin, B. S., An, G., & Morris, M. E. (2008). Biochanin A inhibits breast cancer tumor growth in a murine xenograft model. Pharm Res, 25(9), 2158-2163.

Journal Article, Academic Journal (Published June 2008)

Felmlee, M. A., & Morris, M. E. (2008). Overview of the proton-coupled MCT (SLC16A) family of transporters: characterization, function and role in the transport of the drug of abuse gamma-hydroxybutyric acid. AAPS J, 10(2), 311-321.

Journal Article, Academic Journal (Published May 2008)

Moon, Y. J., Wang, L., DiCenzo, R., & Morris, M. E. (2008). Quercetin pharmacokinetics in humans. Biopharm Drug Dispos, 29(4), 205-217.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2008)

Wang, X., Wang, Q., & Morris, M. E. (2008). Pharmacokinetic interaction between the flavonoid luteolin and gamma-hydroxybutyrate in rats: potential involvement of monocarboxylate transporters. AAPS J, 10(1), 47-55.

Journal Article, Academic Journal (Submitted May 2009)

Telang, U., Ji, Y., & Morris, M. E. (2009). ABC transporters and isothiocyanates: Potential for pharmacokinetic diet-drug interactions. Biopharm Drug Disp.

Journal Article, Academic Journal (Submitted May 2009)

Yang, X., Gandhi, Y. A., Duignan, D. B., & Morris, M. E. (2009). Prediction of Biliary Excretion in Rats and Humans Using. AAPPS Journal.

Journal Article, Academic Journal (Submitted March 2009)

Gandhi, Y. A., & Morris, M. E. (2009). Quantitiative structure-activity relationships for breast cancer resistance protein (ABCG2). AAPS Journal.

Other Intellectual Contributions

Abstract (Published April (2nd Quarter/Spring) 2009)

Jaenecke, K., Stewart, M., Morris, M. E., Brazeau, D. A., & Havard, P. F. (2009). A Semi-Quantitative Comparison of P-glycoprotein Protein Expression in Peripheral Blood Mononuclear Cells Between the Maternal and Fetal Compartments. Accepted to the 2009 APhA Annual Meeting, San Antonio TX, April 3rd - 6th, 2009.. San Antonio TX: 2009 APhA Annual Meeting, San Antonio TX, April 3rd - 6th, 2009..

Qu, Jun (Research Assistant Professor)

Refereed Journal Articles

Journal Article, Academic Journal (Published June 8, 2009)

Duan, X. T., Young, R., Straubinger, R. M., Page, B. J., Cao, J., Wang, H., Yu, H., Canty, J. M., & Qu, J. (2009). A straightforward and highly efficient precipitation/on-pellet digestion procedure coupled to long gradient nano-LC separation and Oribtrap mass spectrometry for the label-free expression profiling of swine heart mitochondria proteome. J. Proteome Res..

Journal Article, Academic Journal (Published March 20, 2009)

Wang, H., Straubinger, R. M., Aletta, J. M., Cau, J., Duan, X. T., Yu, H., & Qu, J. (2009). Accurate localization and relative quantification of arginine methylation using nanoflow liquid chromatography coupled to electron transfer dissociation and orbitrap mass spectrometry. J Am Soc Mass Spectrom, 20, 507-519.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2009)

Yu, A., Qu, J., Felmlee, M. A., Cao, J., & Jiang, X. (2009). Quantitation of human cytochrome P450 2D6 protein with immunoblot and mass spectrometry analysis. Drug Metab Dispos, 37(1), 370-377.

Journal Article, Academic Journal (Published December 12, 2008)

Gaspar, J. R., Qu, J., Straubinger, N. L., & Straubinger, R. M. (2008). Highly selective and sensitive assay for paclitaxel accumulation by tumor cells based on selective solid phase extraction and micro-flow liquid chromatography coupled to mass spectrometry.. Analyst, 133, 1742-8.

Journal Article, Academic Journal (Published October (4th Quarter/Autumn) 7, 2008)

Yu, H., Straubinger, R. M., Cao, J., Wang, H. S., & Qu, J. (2008). Ultra-sensitive quantification of paclitaxel using selective solid-phase extraction in conjunction with reversed-phase capillary liquid chromatography/tandem mass spectrometry. J. Chromatog. A, 1210, 160-167.

Non-Refereed Journal Articles

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2008)

Song, W., Wang, Y., Madden, M. M., Lin, Q., & Qu, J. (2008). A photoinducible 1,3-dipolar cycloaddition reaction for rapid, selective modification of tetrazole-containing proteins. Angew Chem Int Ed Engl, 47(15), 2832-2835.

Journal Article, Academic Journal (Accepted June 30, 2009)

Vagin, V. V., Wohlschlegel, J., Qu, J., Jonsson, Z., Huang, X., Chuma, S., Girard, A., Sachidanandam, R., & Hannon, G. J. (2009). Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction withTudor family members. GENES & DEVELOPMENT.

Journal Article, Professional Journal (Accepted June 30, 2009)

Shah, M. B., Ingram-Smith, C., Cooper, L. L., Qu, J., Meng, Y., Smith, K. S., & Gulick, A. M. (2009). The 2.1 A crystal structure of an acyl-CoA synthetase from Methanosarcina acetivorans reveals an alternate acyl-binding pocket for small branched acyl substrates.. Proteins.

Other Intellectual Contributions

Ramanathan, Murali (Associate Professor)

Refereed Journal Articles

Journal Article, Academic Journal (Published June 2009)

Abraham, A. K., Ramanathan, M., Weinstock-Guttman, B., & Mager, D. E. (2009). Mechanisms of interferon-beta effects on bone homeostasis. Biochem Pharmacol, 77, 1757-1762.

Journal Article, Academic Journal (Published June 1, 2009)

Zivadinov, R., Zorzon, M., Weinstock-Guttman, B., Serafin, M., Bosco, A., Bratina, A., Maggiore, C., Grop, A., Tommasi, M. A., Srinivasaraghavan, B., & Ramanathan, M. (2009). Epstein-Barr virus is associated with grey matter atrophy in multiple sclerosis. Journal of Neurology Neurosurgery Psychiatry, 80(6), 620-625.

Journal Article, Academic Journal (Published April (2nd Quarter/Spring) 30, 2009)

Zivadinov, R., Weinstock-Guttman, B., Zorzon, M., Uxa, L., Serafin, M., Bosco, A., Bratina, A., Maggiore, C., Grop, A., Tommasi, M. A., Srinivasaraghavan, B., & Ramanathan, M. (2009). Gene-environment interactions between HLA B7/A2, EBV antibodies are associated with MRI injury in multiple sclerosis. Journal of Neuroimmunology, 209(1-2), 123-130.

Journal Article, Academic Journal (Published April (2nd Quarter/Spring) 2009)

Kim, T., Hwang, W., Zhang, A., Ramanathan, M., & Sen, S. (2009). Damage Isolation via Strategic Self-destruction: A Case Study in 2D Random Networks. Europhysics Letters, 86 (2009).

Journal Article, Academic Journal (Published March 2009)

Chanda, P., Sucheston, L. E., Zhang, A., & Ramanathan, M. (2009). The Interaction Index, a Novel Information-Theoretic Metric For Prioritizing Interacting Genetic Variations and Environmental Factors. the European Journal of Human Genetics (EJHG), March 2009.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2009)

Forum, D., Ramanathan, M., Fink, C. S., Wilding, G. E., Weinstock-Guttman, B., & Awad, A. B. (2009). Comparison of the immunomodulatory effects of the plant sterol beta-sitosterol to simvastatin in peripheral blood cells from multiple sclerosis patients. International J Immunopharmacology, 9, 153-157.

Journal Article, Academic Journal (Published December 15, 2008)

Weinstock-Guttman, B., Bhasi, K., Badgett, D., Tamaño-Blanco, M., Minhas, M., Feichter, J., Patrick, K., Munschauer, F. E., Bakshi, R., & Ramanathan, M. (2008). Genomic effects of once-weekly, intramuscular interferon-beta1a treatment after the first dose and on chronic dosing: Relationships to 5-year clinical outcomes in multiple sclerosis patients. Journal of Neuroimmunology, 205(1-2), 113-125.

Journal Article, Academic Journal (Published September 18, 2008)

Cho, Y., Shi, L., Ramanathan, M., & Zhang, A. (2008). A Probabilistic Framework to Predict Protein Function from Interaction Data Integrated with Semantic Knowledge. BMC Bioinformatics.

Journal Article, Academic Journal (Published September 14, 2008)

Weinstock-Guttman, B., Miller, C., Yeh, E. A., Stosic, M., Umhauer, M., Batra, N., Munschauer, F. E., Zivadinov, R., & Ramanathan, M. (2008). Neuromyelitis optica immunoglobulins (NMO IgG) as a marker of disease activity and response to therapy in patients with neuromyelitis optica. Multiple Sclerosis, 1061-1067.

Journal Article, Academic Journal (Published September 9, 2008)

Chanda, P., Sucheston, L. E., Zhang, A., Brazeau, D. A., Freudenheim, J. L., Ambrosone, C., & Ramanathan, M. (2008). AMBIENCE: A Novel Approach and Efficient Algorithm for Identifying Informative Genetic and Environment Interactions Associated with Complex Phenotypes. Genetics.

Journal Article, Academic Journal (Published August 15, 2008)

Zivadinov, R., Munschauer, F. E., Ramanathan, M., Benedict, R. H., & Weinstock-Guttman, B. (2008). Clinical efficacy, effects on MRI and tolerability of weekly intramuscular interferon-beta-1a in patients with MS and CIS. Drugs Today, 44(8), 610-613.

Journal Article, Professional Journal (Published June 2008)

Chanda, P., Sucheston, L. E., Zhang, A., Brazeau, D., Freudenheim, J. L., Ambrosone, C., & Ramanathan, M. (2008). Ambience: A novel algorithm for identifying and visualizing informative genetic and environment interactions associated with complex disease phenotypes. Genetics, 180, 1191-210.

Journal Article, Academic Journal (Published May 15, 2008)

Grazioli, E., Zivadinov, R., Weinstock-Guttman, B., Lincoff, N. S., Baier, M., Wong, J. R., Hussein, S., Cox, J. L., Hojnacki, D., & Ramanathan, M. (2008). Retinal nerve fiber layer thickness is associated with brain MRI outcomes in multiple sclerosis. Journal of Neurological Sciences, 268(1-2).

Journal Article, Academic Journal (Accepted May 30, 2009)

Yeh, E. A., Weinstock-Guttman, B., Lincoff, N. S., Reynolds, J. D., Weinstock, A. L., Madurai, N., Agarwal, N., Buch, P., Karpinski, M., & Ramanathan, M. (2009). Retinal nerve fiber thickness in inflammatory demyelinating diseases of childhood onset. Multiple Sclerosis.

Journal Article, Academic Journal (September 15, 2008)

Weinstock-Guttman, B., Ramanathan, M., & Zivadinov, R. (2008). Interferon-<beta> treatment for relapsing multiple sclerosis. Expert Opinion in Biological Therapies, 1437-1447.

Journal Article, Academic Journal (July (3rd Quarter/Summer) 9, 2008)

Hwang, W., Ramanathan, M., & Zhang, A. (2008). Identification of Information Flow-Modulating Drug Targets: A Novel Bridging Paradigm for Drug Discovery. Clinical Pharmacology and Therapeutics, 84(5), 563-572.

Conference Proceedings

Conference Proceeding (Published November 3, 2008)

Kim, T., Hwang, W., Zhang, A., Sen, S., & Ramanathan, M. (2008). Multi-Agent Model Analysis of the Containment Strategy for Avian Influenza (AI) in South Korea. 2008 IEEE International Conference on Bioinformatics and Biomedicine.

Conference Proceeding (Published October (4th Quarter/Autumn) 8, 2008)

Chanda, P., Zhang, A., & Ramanathan, M. (2008). A Novel Information Theoretic Method for Detecting Gene-Gene Interactions in Complex Diseases. the 8th IEEE International Conference on BioInformatics and BioEngineering (BIBE2008).

Conference Proceeding (Published August 26, 2008)

Hwang, W., Kim, T., Ramanathan, M., & Zhang, A. (2008). Bridging Centrality: Graph Mining from Element Level to Group Level. the 14th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining.

Conference Proceeding (Published August 24, 2008)

Chanda, P., Zhang, A., Sucheston, L. E., & Ramanathan, M. (2008). Information Theoretic Methods for Detecting Multiple Loci Associated with Complex Diseases. 8th International Workshop on Data Mining in Bioinformatics (BIOKDD08).

Schentag Pharm D, Jerome J. (Professor)

Refereed Journal Articles

Journal Article, Professional Journal (Published April (2nd Quarter/Spring) 2008)

Monte, S. V., Albanese, N. P., Slazak, E. M., Schentag, J. J., & Paladino, J. A. (2008). Costs of treating lower respiratory tract infections. American Journal of Managed Care, 14, 190-196.

Non-Refereed Journal Articles

Journal Article, Professional Journal (Published January (1st Quarter/Winter) 2009)

File, T. M., Monte, S. V., & Schentag, J. J. (2009). A disease model descriptive of progression between chronic obstructive pulmonary disease exacerbations and community-acquired pneumonia: roles for underlying lung disease and the pharmacokinetics/pharmacodynamics of the antibiotic.. Int J Antimicrob Agents, 33(1), 58-64.

Journal Article, Professional Journal (Published June 15, 2008)

Paladino, J. A., Sunderlin, J. E., Singer, M. E., Adelman, M. H., & Schentag, J. J. (2008). Am J Health Syst Pharm, 65(12), 1154-9.

Journal Article, Professional Journal (Published June 15, 2008)

Paladino, J. A. (2008). of extended-spectrum beta-lactams on gram-negative bacterial resistance. Am J Health Syst Pharm, 65(12), 1154-9.

Journal Article, Academic Journal (Published April (2nd Quarter/Spring) 2008)

Monte, S. V., Paolini, N. M., Slazak, E. M., Schentag, J. J., & Paladino, J. A. (2008). Costs of treating lower respiratory tract infections. Am J Manag Care, 14(4), 190-196.

Journal Article, Professional Journal (Published April (2nd Quarter/Spring) 2008)

Monte, S. V., Paolini, N. M., Slazak, E. M., Schentag, J. J., & Paladino, J. A. (2008). Costs of treating lower respiratory tract infections.. Am J Manag Care, 14(4), 190-6.

Journal Article, Professional Journal (Published April (2nd Quarter/Spring) 2008)

McKinnon, P. S., Paladino, J. A., & Schentag, J. J. (2008). Evaluation of area under the inhibitory curve (AUIC) and time above the minimum inhibitory concentration (T>MIC) as predictors of outcome for cefepime and ceftazidime in serious bacterial infections. Int J Antimicrob Agents, 31(4), 345-51.

Journal Article, Professional Journal (Published April (2nd Quarter/Spring) 2008)

McKinnon, P. S., Paladino, J. A., & Schentag, J. J. (2008). Evaluation of area under the inhibitory curve (AUIC) and time above the minimum inhibitory concentration (T>MIC) as predictors of outcome for cefepime and ceftazidime in serious bacterial infections.. Int J Antimicrob Agents, 31(4), 345-51.

Journal Article, Professional Journal (Published February 15, 2008)

Paladino, J. A., & Schentag, J. J. (2008). The economics of Clostridium difficile-associated disease for providers and payers. Clin Infect Dis, 46(4), 505-6.

Journal Article, Professional Journal (Published January (1st Quarter/Winter) 2008)

Noskin, G. A., Rubin, R. J., & Schentag, J. J. (2008). Budget impact analysis of rapid screening for Staphylococcus aureus colonization among patients undergoing elective surgery in US hospitals. Control Hosp Epidemiol, 29(1), 16-24.

Journal Article, Professional Journal (Published January (1st Quarter/Winter) 2008)

Kiem, S., & Schentag, J. J. (2008). Interpretation of antibiotic concentration ratios measured in epithelial lining fluid.. Antimicrob Agents Chemother, 52(2), 24-36.

Other Intellectual Contributions

Manuscript (Published 2008)

Schentag, J. J. (2008). What can we learn from the time course of untreated and partially treated community-onset Streptococcus pneumoniae pneumonia? A clinical perspective on superiority and noninferiority trial designs for mild community-acquired pneumonia. (ed., vol. 47, pp. S157-65). Chicago, IL: Chicago Journals.

Manuscript (Published October (4th Quarter/Autumn) 2008)

McKinnon, P. S. (2008). In Schentag, J. J. (Ed.), Evaluation of area under the inhibitory curve (AUIC) and time above the minimum inhibitory concentration (T>MIC) as predictors of outcome for cefepime and ceftazidime in serious bacterial infections (4th ed., vol. 31, pp. 345-51). Evaluation of area under the inhibitory curve (AUIC) and time above the minimum inhibitory concentration (T>MIC) as predictors of outcome for cefepime and ceftazidime in serious bacterial infections..

Manuscript (Published September 2008)

Schentag, J. J. (2008). Vancomycin in vitro bactericidal activity and its relationship to efficacy in clearance of methicillin-resistant Staphylococcus aureus bacteremia. (ed., vol. 47, pp. D157-65). Clin Infect Dis.

Manuscript (Published April (2nd Quarter/Spring) 2008)

Paladino, J. A., & Schentag, J. J. (2008). The economics of Clostridium difficile-associated disease for providers and payers. (4th ed., vol. 46, pp. 505-6). Chicago, IL: Clin Infect Dis.

Comment (Published February 2008)

Paladino, J. A., & Schentag, J. J. (2008). The economics of Clostridium difficile-associated disease for providers and payers (4th ed., vol. 46, pp. 505-506). Clin Infect Dis.

Manuscript (Published January (1st Quarter/Winter) 2008)

Noskin, G. A., Rubin, R. J., & Schentag, J. J. (2008). Budget impact analysis of rapid screening for Staphylococcus aureus colonization among patients undergoing elective surgery in US hospitals. (1st ed., vol. 29, pp. 16-24). Chicago, Illinois: Control Hosp Epidemiol..

(December 1, 2008)

File, T. M., & Schentag, J. J. (2008). What can we learn from the time course of untreated and partially treated community-onset Streptococcus pneumoniae pneumonia? A clinical perspective on superiority and noninferiority trial designs for mild community-acquired pneumonia. (3rd ed., vol. 47, pp. S157-65). Arlington vA: Clin Infect Dis..

Straubinger, Robert M. (Professor)

Refereed Journal Articles

Journal Article, Academic Journal (Published June 8, 2009)

Duan, X. T., Young, R., Straubinger, R. M., Page, B. J., Cao, J., Wang, H., Yu, H., Canty, J. M., & Qu, J. (2009). A straightforward and highly efficient precipitation/on-pellet digestion procedure coupled to long gradient nano-LC separation and Oribtrap mass spectrometry for the label-free expression profiling of swine heart mitochondria proteome. J. Proteome Res..

Journal Article, Academic Journal (Published March 20, 2009)

Wang, H., Straubinger, R. M., Aletta, J. M., Cau, J., Duan, X. T., Yu, H., & Qu, J. (2009). Accurate localization and relative quantification of arginine methylation using nanoflow liquid chromatography coupled to electron transfer dissociation and orbitrap mass spectrometry. J Am Soc Mass Spectrom, 20, 507-519.

Journal Article, Academic Journal (Published December 12, 2008)

Gaspar, J. R., Qu, J., Straubinger, N. L., & Straubinger, R. M. (2008). Highly selective and sensitive assay for paclitaxel accumulation by tumor cells based on selective solid phase extraction and micro-flow liquid chromatography coupled to mass spectrometry.. Analyst, 133, 1742-8.

Journal Article, Academic Journal (Published October (4th Quarter/Autumn) 7, 2008)

Yu, H., Straubinger, R. M., Cao, J., Wang, H. S., & Qu, J. (2008). Ultra-sensitive quantification of paclitaxel using selective solid-phase extraction in conjunction with reversed-phase capillary liquid chromatography/tandem mass spectrometry. J. Chromatog. A, 1210, 160-167.

Journal Article, Academic Journal (Published September 2008)

Ramani, K., Miclea, R. D., Gaitonde, P., Straubinger, R. M., Balu-Iyer, S. V. (2008). Passive Transfer of Polyethyleneglycol to Liposomal-Recombinant Human FVIII Enhances its Efficacy in a Murine Model for Hemophilia A. Journal of Pharmaceutical Sciences, 97(9), 3753-3764.

Journal Article, Academic Journal (Published April (2nd Quarter/Spring) 2008)

Ramani, K., Miclea, R. D., Purohit, V. S., Straubinger, R. M., Mager, D. E., & Balu-Iyer, S. V. (2008). Phosphatidylserine Containing Liposomes reduce Immunogenicity of Recombinant Human Factor VIII in a Murine Model of Hemophilia A. Journal. Pharmaceutical Sciences, 97, 1386-1397.

Yu, Aiming (Assistant Professor)

Book Chapters

Book, Chapter in Scholarly Book-New (Published April (2nd Quarter/Spring) 2009)

Yu, A., Shen, H., Jiang, X., Wu, C. (2009). Metabolism and drug-drug interactions of psychoactive harmaline and 5-methoxy-N,N-dimethyltryptamine. In Proceedings of the 17th International Symposium on Microsomes and Drug Oxidations.

Refereed Journal Articles

Journal Article, Academic Journal (Published September 30, 2009)

Pan, Y., Gao, W., & Yu, A. (2009). MicroRNAs regulate CYP3A4 expression via direct and indirect targeting. Drug Metab Dispos, 37(10), 2112-2117.

Journal Article, Academic Journal (Published August 31, 2009)

Wu, C., Jiang, X., Shen, H., & Yu, A. (2009). Effects of CYP2D6 Status on Harmaline Metabolism, Pharmacokinetics and Pharmacodynamics, and a Pharmacogenetics-Based Pharmacokinetic Model. Biochem Pharmacol, 78(6), 617-624.

Journal Article, Academic Journal (Published May 2009)

Pan, Y., Morris, M. E., & Yu, A. (2009). MicroRNA-328 Negatively Regulates the Expression of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Cancer Cells. Mol Pharmacol, 75(6), 1374-1379.

Journal Article, Academic Journal (Published April (2nd Quarter/Spring) 2009)

Shen, H., Jiang, X., & Yu, A. (2009). Development of a LC-MS/MS method to analyze 5-methoxy-N,N-dimethyltryptamine and bufotenine, and application to pharmacokinetic study. Bioanalysis, 1(1), 87-95.

Journal Article, Academic Journal (Published March 2009)

Jiang, X., Shen, H., & Yu, A. (2009). Pinoline may be used as a probe for CYP2D6 activity. Drug Metab Dispos, 37(3), 443-446.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 2009)

Yu, A., Qu, J., Felmlee, M. A., Cao, J., & Jiang, X. (2009). Quantitation of human cytochrome P450 2D6 protein with immunoblot and mass spectrometry analysis. Drug Metab Dispos, 37(1), 370-377.

Journal Article, Academic Journal (Published January (1st Quarter/Winter) 1, 2009)

Zhang, W., Tu, Y., Haining, R. L., & Yu, A. (2009). Expression and functional analysis of CYP2D6.24, CYP2D6.26, CYP2D6.27 and CYP2D7 isozymes. Drug Metab Dispos, 37(1), 1-4.

Journal Article, Academic Journal (Published June 2008)

Yu, A. (2008). Indolealkylamines: Biotransformations and potential drug-drug interactions. AAPS J, 10(2), 242-253.

Journal Article, Academic Journal (Published February 2008)

Felmlee, M. A., Lon, H. K., Gonzalez, F. J., & Yu, A. (2008). Cytochrome P450 expression and regulation in CYP3A4/CYP2D6 double transgenic humanized mice. Drug Metab Dispos, 36(2), 435-441.

Journal Article, Academic Journal (Accepted September 30, 2009)

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Journal Article, Academic Journal (Accepted September 30, 2009)

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