Pharmaceutical Sciences Publications

Dr. Joseph Balthasar

Chen J, Lu Q, Balthasar JP, Balthasar J; Mathematical modeling of topotecan pharmacokinetics and toxicodynamics in mice. J Pharmacokinet Pharmacodyn; 2007 Dec; 34(6). Journal Article

Garg A, Balthasar JP, Balthasar J; Physiologically-based pharmacokinetic (PBPK) model to predict IgG tissue kinetics in wild-type and FcRn-knockout mice. J Pharmacokinet Pharmacodyn; 2007 Oct; 34(5). Journal Article

Deng R, Balthasar JP, Balthasar J; Pharmacokinetic/pharmacodynamic modeling of IVIG effects in a murine model of immune thrombocytopenia. J Pharm Sci; 2007 Jun; 96(6). Journal Article

Balthasar J, Chen J; Development and characterization of high-affinity anti-topotecan IgG and fab fragments ; 2007 Jun; 6.5.

Deng R, Balthasar JP, Balthasar J; Comparison of the effects of antibody-coated liposomes, IVIG, and anti-RBC immunotherapy in a murine model of passive chronic immune thrombocytopenia. Blood; 2007 Mar; 109(6). Comparative Study

Shin BS, Choi JW, Balthasar JP, Hong DK, Kim JJ, Yoo SD, Balthasar J; Determination of roxatidine in human plasma by liquid chromatography/electrospray mass spectrometry and application to a clinical pharmacokinetic study. Rapid Commun Mass Spectrom; 2007 Jan; 21(3). Journal Article

Dr. Sathy Balu-Iyer

Miclea RD, Varma PR, Peng A, Balu-Iyer SV; Development and characterization of lipidic cochleate containing recombinant factor VIII. Biochim Biophys Acta; 2007 Nov; 1768(11). Journal Article

Ramani K, Miclea RD, Purohit VS, Mager DE, Straubinger RM, Balu-Iyer SV; Phosphatidylserine containing liposomes reduce immunogenicity of recombinant human factor VIII (rFVIII) in a murine model of hemophilia A. J Pharm Sci; 2007 Aug. Journal Article

Miclea RD, Purohit VS, Balu-Iyer SV; O-phospho-L-serine, multi-functional excipient for B domain deleted recombinant factor VIII. AAPS J; 2007 Jun; 9(2). In Vitro

Balu-Iyer SV, Purohit VS, Miclea RD; Formulation and Delivery Issues of Therapeutic Proteins ; 2007 Jun; 6.2.

K Ramani, RD Miclea, P Gaitonde, RM Straubinger, SV Balu-Iyer; Passive Transfer of Polyethyleneglycol to Liposomal-Recombinant Human FVIII Enhances its Efficacy in a Murine Model for Hemophilia A Journal of Pharmaceutical Sciences; 2007 Jan.

Dr. Javier Blanco

Vicente-Serrano J, Caballero ML, Rodr�guez-P�rez R, Carretero P, P�rez R, Blanco JG, Juste S, Moneo I; Sensitization to serum albumins in children allergic to cow's milk and epithelia. Pediatr Allergy Immunol; 2007 Sep; 18(6). Journal Article

Lakhman SS, Chen X, Gonzalez-Covarrubias V, Schuetz EG, Blanco JG; Functional characterization of the promoter of human carbonyl reductase 1 (CBR1). Role of XRE elements in mediating the induction of CBR1 by ligands of the aryl hydrocarbon receptor. Mol Pharmacol; 2007 Jun; 72(3). Journal Article

Gonzalez-Covarrubias V, Ghosh D, Lakhman SS, Pendyala L, Blanco JG; A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity. Drug Metab Dispos; 2007 Jun; 35(6). Journal Article

Weiss JR, Baer MR, Ambrosone CB, Blanco JG, Hutson A, Ford LA, Moysich KB; Concordance of pharmacogenetic polymorphisms in tumor and germ line DNA in adult patients with acute myeloid leukemia. Cancer Epidemiol Biomarkers Prev; 2007 May; 16(5). Journal Article

Dr. Kathleen Boje

Page NA, Paganelli M, Boje KM, Fung HL; An interactive lesson in acid/base and pro-drug chemistry using sodium gamma-hydroxybutyrate and commercial test coasters. Am J Pharm Educ; 2007 Jun; 71(3). Journal Article

Raybon JJ, Boje KM; Pharmacokinetics and pharmacodynamics of gamma-hydroxybutyric acid during tolerance in rats: effects on extracellular dopamine. J Pharmacol Exp Ther; 2007 Mar; 320(3). Journal Article

Bhattacharya I, Boje KM; Feasibility of D-glucuronate to enhance gamma-hydroxybutyric acid metabolism during gamma-hydroxybutyric acid toxicity: pharmacokinetic and pharmacodynamic studies. Biopharm Drug Dispos; 2007 Jan; 28(1). Journal Article

Bhattacharya I, Boje KM; Potential gamma-hydroxybutyric acid (GHB) drug interactions through blood-brain barrier transport inhibition: a pharmacokinetic simulation-based evaluation. J Pharmacokinet Pharmacodyn; 2006 Oct; 33(5). Journal Article

Bhattacharya I, Raybon JJ, Boje KM; Alterations in neuronal transport but not blood-brain barrier transport are observed during gamma-hydroxybutyrate (GHB) sedative/hypnotic tolerance. Pharm Res; 2006 Sep; 23(9). In Vitro

Dr. Daniel Brazeau

Tsai WJ, McCormick KM, Brazeau DA, Brazeau GA; Estrogen effects on skeletal muscle insulin-like growth factor 1 and myostatin in ovariectomized rats. Exp Biol Med (Maywood); 2007 Nov; 232(10). Journal Article

Chanda P, Zhang A, Brazeau D, Sucheston L, Freudenheim JL, Ambrosone C, Ramanathan M, Brazeau DA; Information-theoretic metrics for visualizing gene-environment interactions. Am J Hum Genet; 2007 Nov; 81(5). Journal Article

Renzi SE, Krzeminski MA, Sauberan MM, Brazeau DA, Brazeau GA; Prepharmacy years in college and academic performance in a professional program. Am J Pharm Educ; 2007 Aug; 71(4). Comparative Study

Moon YJ, Zhang S, Brazeau DA, Morris ME; Effects of the flavonoid biochanin A on gene expression in primary human hepatocytes and human intestinal cells. Mol Nutr Food Res; 2007 Mar; 51(3). Journal Article

Moon YJ, Brazeau DA, Morris ME; Effects of flavonoids genistein and biochanin a on gene expression and their metabolism in human mammary cells. Nutr Cancer; 2007 Jan; 57(1). Journal Article

Brazeau DA; Pharmacogenomics of Warfarin Therapy for Venous Clinical Laboratories LabQ series; 2007 Jan; 1.

Brazeau DA, Brazeau GA; A required course in human genomics, pharmacogenomics, and bioinformatics. Am J Pharm Educ; 2006 Dec; 70(6). Journal Article

Bhasi K, Zhang L, Brazeau D, Zhang A, Ramanathan M; Information-theoretic identification of predictive SNPs and supervised visualization of genome-wide association studies. Nucleic Acids Res; 2006 Aug; 34(14). Evaluation Studies

Dr. Gayle Brazeau

Tsai WJ, McCormick KM, Brazeau DA, Brazeau GA; Estrogen effects on skeletal muscle insulin-like growth factor 1 and myostatin in ovariectomized rats. Exp Biol Med (Maywood); 2007 Nov; 232(10). Journal Article

Kranz H, Yilmaz E, Brazeau GAYLE, Bodmeier R; In Vitro and In Vivo Drug Release from a Novel In Situ Forming Drug Delivery System. Pharm Res; 2007 Oct. Journal Article

Rungseevijitprapa W, Brazeau GA, Simkins JW, Bodmeier R; Myotoxicity studies of O/W-in situ forming microparticle systems. Eur J Pharm Biopharm; 2007 Oct. Journal Article

Smesny AL, Williams JS, Brazeau GA, Weber RJ, Matthews HW, Das SK; Barriers to scholarship in dentistry, medicine, nursing, and pharmacy practice faculty. Am J Pharm Educ; 2007 Oct; 71(5). Journal Article

Renzi SE, Krzeminski MA, Sauberan MM, Brazeau DA, Brazeau GA; Prepharmacy years in college and academic performance in a professional program. Am J Pharm Educ; 2007 Aug; 71(4). Comparative Study

Brazeau GA; Teaching, practice and technology. Am J Pharm Educ; 2007 Jun; 71(3). Journal Article

Brazeau DA; Pharmacogenomics of Warfarin Therapy for Venous Clinical Laboratories LabQ series; 2007 Jan; 1.

Brazeau DA, Brazeau GA; A required course in human genomics, pharmacogenomics, and bioinformatics. Am J Pharm Educ; 2006 Dec; 70(6). Journal Article

Brazeau GA, Van Tyle JH; Sabbaticals: the key to sharpening our professional skills as educators, scientists, and clinicians. Am J Pharm Educ; 2006 Oct; 70(5). Journal Article

Dr. Walter Conway

Conway WD; Service life of counter-current chromatography coils. J Chromatogr A; 2007 Jun; 1151(1-2). Journal Article

Dr. Debra Dubois

Hazra A, Pyszczynski N, DuBois DC, Almon RR, Jusko WJ; Modeling receptor/gene-mediated effects of corticosteroids on hepatic tyrosine aminotransferase dynamics in rats: dual regulation by endogenous and exogenous corticosteroids. J Pharmacokinet Pharmacodyn; 2007 Oct; 34(5). Journal Article

Yao Z, Dubois DC, Almon RR, Jusko WJ; Pharmacokinetic/pharmacodynamic modeling of corticosterone suppression and lymphocytopenia by methylprednisolone in rats. J Pharm Sci; 2007 Sep. Journal Article

Hazra A, Pyszczynski N, DuBois DC, Almon RR, Jusko WJ; Pharmacokinetics of methylprednisolone after intravenous and intramuscular administration in rats. Biopharm Drug Dispos; 2007 Sep; 28(6). Journal Article

Almon RR, DuBois DC, Yao Z, Hoffman EP, Ghimbovschi S, Jusko WJ; Microarray analysis of the temporal response of skeletal muscle to methylprednisolone: comparative analysis of two dosing regimens. Physiol Genomics; 2007 Aug; 30(3). Comparative Study

Yang E, Simcha D, Almon RR, Dubois DC, Jusko WJ, Androulakis IP; Context specific transcription factor prediction. Ann Biomed Eng; 2007 Jun; 35(6). Journal Article

Hazra A, DuBois DC, Almon RR, Jusko WJ; Assessing the dynamics of nuclear glucocorticoid-receptor complex: adding flexibility to gene expression modeling. J Pharmacokinet Pharmacodyn; 2007 Jun; 34(3). Journal Article

Almon RR, DuBois DC, Jusko WJ; A microarray analysis of the temporal response of liver to methylprednisolone: a comparative analysis of two dosing regimens. Endocrinology; 2007 May; 148(5). Comparative Study

Yao Z, Zhao B, Hoffman EP, Ghimbovschi S, DuBois DC, Almon RR, Jusko WJ; Application of scaling factors in simultaneous modeling of microarray data from diverse chips. Pharm Res; 2007 Apr; 24(4). Comparative Study

Ms. Jill Fiedler-Kelly

No Recent Publications

Dr. Ho Leung Fung

Turowski SG, Jank KE, Fung HL, Fung H; Inactivation of hepatic enzymes by inhalant nitrite--in vivo and in vitro studies. AAPS J; 2007 Jul; 9(3). Journal Article

Fung HL, Tran DC, Fung H; Effects of inhalant nitrites on VEGF expression: a feasible link to Kaposi's sarcoma? J Neuroimmune Pharmacol; 2006 Sep; 1(3). Journal Article

Dr. Wenqing Gao

Gao W, Dalton JT; Expanding the therapeutic use of androgens via selective androgen receptor modulators (SARMs). Drug Discov Today; 2007 Mar; 12(5-6). Journal Article

Kearbey JD, Gao W, Narayanan R, Fisher SJ, Wu D, Miller DD, Dalton JT; Selective Androgen Receptor Modulator (SARM) treatment prevents bone loss and reduces body fat in ovariectomized rats. Pharm Res; 2007 Feb; 24(2). Journal Article

Gao W, Dalton JT; Ockham's razor and selective androgen receptor modulators (SARMs): are we overlooking the role of 5alpha-reductase? Mol Interv; 2007 Feb; 7(1). Journal Article

Gao W, Kim J, Dalton JT; Pharmacokinetics and pharmacodynamics of nonsteroidal androgen receptor ligands. Pharm Res; 2006 Aug; 23(8). Journal Article

Dr. William Jusko

Woo S, Krzyzanski W, Duliege AM, Stead RB, Jusko WJ; Population Pharmacokinetics and Pharmacodynamics of Peptidic Erythropoiesis Receptor Agonist (ERA) in Healthy Volunteers. J Clin Pharmacol; 2008 Jan; 48(1). Journal Article

Woo S, Krzyzanski W, Jusko WJ; Target-mediated pharmacokinetic and pharmacodynamic model of recombinant human erythropoietin (rHuEPO). J Pharmacokinet Pharmacodyn; 2007 Dec; 34(6). Journal Article

Woo S, Krzyzanski W, Duliege AM, Stead RB, Jusko WJ; Population Pharmacokinetics and Pharmacodynamics of Peptidic Erythropoiesis Receptor Agonist (ERA) in Healthy Volunteers. J Clin Pharmacol; 2007 Nov. Journal Article

Hazra A, Pyszczynski N, DuBois DC, Almon RR, Jusko WJ; Modeling receptor/gene-mediated effects of corticosteroids on hepatic tyrosine aminotransferase dynamics in rats: dual regulation by endogenous and exogenous corticosteroids. J Pharmacokinet Pharmacodyn; 2007 Oct; 34(5). Journal Article

Yao Z, Dubois DC, Almon RR, Jusko WJ; Pharmacokinetic/pharmacodynamic modeling of corticosterone suppression and lymphocytopenia by methylprednisolone in rats. J Pharm Sci; 2007 Sep. Journal Article

Hazra A, Pyszczynski N, DuBois DC, Almon RR, Jusko WJ; Pharmacokinetics of methylprednisolone after intravenous and intramuscular administration in rats. Biopharm Drug Dispos; 2007 Sep; 28(6). Journal Article

Woo S, Jusko WJ; Interspecies comparisons of pharmacokinetics and pharmacodynamics of recombinant human erythropoietin. Drug Metab Dispos; 2007 Sep; 35(9). Journal Article

Almon RR, DuBois DC, Yao Z, Hoffman EP, Ghimbovschi S, Jusko WJ; Microarray analysis of the temporal response of skeletal muscle to methylprednisolone: comparative analysis of two dosing regimens. Physiol Genomics; 2007 Aug; 30(3). Comparative Study

Yang E, Simcha D, Almon RR, Dubois DC, Jusko WJ, Androulakis IP; Context specific transcription factor prediction. Ann Biomed Eng; 2007 Jun; 35(6). Journal Article

Hazra A, DuBois DC, Almon RR, Jusko WJ; Assessing the dynamics of nuclear glucocorticoid-receptor complex: adding flexibility to gene expression modeling. J Pharmacokinet Pharmacodyn; 2007 Jun; 34(3). Journal Article

Samtani MN, Jusko WJ; Quantification of dexamethasone and corticosterone in rat biofluids and fetal tissue using highly sensitive analytical methods: assay validation and application to a pharmacokinetic study. Biomed Chromatogr; 2007 Jun; 21(6). Evaluation Studies

Hong Y, Mager DE, Blum RA, Jusko WJ; Population pharmacokinetic/pharmacodynamic modeling of systemic corticosteroid inhibition of whole blood lymphocytes: modeling interoccasion pharmacodynamic variability. Pharm Res; 2007 Jun; 24(6). Journal Article

Almon RR, DuBois DC, Jusko WJ; A microarray analysis of the temporal response of liver to methylprednisolone: a comparative analysis of two dosing regimens. Endocrinology; 2007 May; 148(5). Comparative Study

Yao Z, Zhao B, Hoffman EP, Ghimbovschi S, DuBois DC, Almon RR, Jusko WJ; Application of scaling factors in simultaneous modeling of microarray data from diverse chips. Pharm Res; 2007 Apr; 24(4). Comparative Study

Wetzler M, Earp JC, Brady MT, Keng MK, Jusko WJ; Synergism between arsenic trioxide and heat shock protein 90 inhibitors on signal transducer and activator of transcription protein 3 activity--pharmacodynamic drug-drug interaction modeling. Clin Cancer Res; 2007 Apr; 13(7). Journal Article

Mager DE, Jusko WJ; Mechanistic pharmacokinetic/pharmacodynamic models II. ; 2007 Mar; 23.

Jin JY, Jusko WJ; Pharmacogenomics and Pharmacokinetic/Pharmacodynamic Modeling ; 2007 Mar; 19.

Hazra A, Krzyzanski W, Jusko WJ; Mathematical assessment of properties of precursor-dependent indirect pharmacodynamic response models. J Pharmacokinet Pharmacodyn; 2006 Dec; 33(6). Journal Article

Woo S, Krzyzanski W, Jusko WJ; Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after intravenous and subcutaneous administration in rats. J Pharmacol Exp Ther; 2006 Dec; 319(3). Journal Article

Krzyzanski W, Dmochowski J, Matsushima N, Jusko WJ; Assessment of dosing impact on intra-individual variability in estimation of parameters for basic indirect response models. J Pharmacokinet Pharmacodyn; 2006 Oct; 33(5). Journal Article

Meno-Tetang GM, Li H, Mis S, Pyszczynski N, Heining P, Lowe P, Jusko WJ; Physiologically based pharmacokinetic modeling of FTY720 (2-amino-2[2-(-4-octylphenyl)ethyl]propane-1,3-diol hydrochloride) in rats after oral and intravenous doses. Drug Metab Dispos; 2006 Sep; 34(9). Journal Article

Schwab M, Coksaygan T, Samtani MN, Jusko WJ, Nathanielsz PW; Kinetics of betamethasone and fetal cardiovascular adverse effects in pregnant sheep after different doses. Obstet Gynecol; 2006 Sep; 108(3 Pt). Comparative Study

Dr. Thomas Kalman

No Recent Publications

Dr. Wojciech Krzyzanski

Dr. Sukwinder Lakhman

No Recent Publications

Dr. Gerhard Levy

No Recent Publications

Dr. Donald Mager

Gengo FM, Rubin L, Robson M, Rainka M, Gengo MF, Mager DE, Bates V; Effects of Ibuprofen on the Magnitude and Duration of Aspirin's Inhibition of Platelet Aggregation: Clinical Consequences in Stroke Prophylaxis. J Clin Pharmacol; 2008 Jan; 48(1). Journal Article

Siluk D, Mager DE, Gronich N, Abernethy D, Wainer IW; HPLC-atmospheric pressure chemical ionization mass spectrometric method for enantioselective determination of R,S-propranolol and R,S-hyoscyamine in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci; 2007 Nov; 859(2). Journal Article

Mager DE, Kobrinsky E, Masoudieh A, Maltsev A, Abernethy DR, Soldatov NM; Analysis of functional signaling domains from fluorescence imaging and the two-dimensional continuous wavelet transform. Biophys J; 2007 Oct; 93(8). Journal Article

Cao YJ, Mager DE, Simonsick EM, Hilmer SN, Ling SM, Windham BG, Crentsil V, Yasar S, Fried LP, Abernethy DR; Physical and Cognitive Performance and Burden of Anticholinergics, Sedatives, and ACE Inhibitors in Older Women. Clin Pharmacol Ther; 2007 Aug. Journal Article

Ramani K, Miclea RD, Purohit VS, Mager DE, Straubinger RM, Balu-Iyer SV; Phosphatidylserine containing liposomes reduce immunogenicity of recombinant human factor VIII (rFVIII) in a murine model of hemophilia A. J Pharm Sci; 2007 Aug. Journal Article

Abraham AK, Krzyzanski W, Mager DE; Partial derivative-based sensitivity analysis of models describing target-mediated drug disposition. AAPS J; 2007 Jun; 9(2). Journal Article

Hong Y, Mager DE, Blum RA, Jusko WJ; Population pharmacokinetic/pharmacodynamic modeling of systemic corticosteroid inhibition of whole blood lymphocytes: modeling interoccasion pharmacodynamic variability. Pharm Res; 2007 Jun; 24(6). Journal Article

Mager DE, Abernethy DR; Use of wavelet and fast Fourier transforms in pharmacodynamics. J Pharmacol Exp Ther; 2007 May; 321(2). Journal Article

Hilmer SN, Mager DE, Simonsick EM, Cao Y, Ling SM, Windham BG, Harris TB, Hanlon JT, Rubin SM, Shorr RI, Bauer DC, Abernethy DR; A drug burden index to define the functional burden of medications in older people. Arch Intern Med; 2007 Apr; 167(8). Journal Article

Mager DE, Jusko WJ; Mechanistic pharmacokinetic/pharmacodynamic models II. ; 2007 Mar; 23.

O'Connor R, O'Leary M, Ballot J, Collins CD, Kinsella P, Mager DE, Arnold RD, O'Driscoll L, Larkin A, Kennedy S, Fennelly D, Clynes M, Crown J; A phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancer. Cancer Chemother Pharmacol; 2007 Jan; 59(1). Clinical Trial, Phase I

Mager DE; Quantitative structure-pharmacokinetic/pharmacodynamic relationships. Adv Drug Deliv Rev; 2006 Nov; 58(12-13). Journal Article

Dr. Marilyn Morris

Wang Q, Lu Y, Morris ME; Monocarboxylate transporter (MCT) mediates the transport of gamma-hydroxybutyrate in human kidney HK-2 cells. Pharm Res; 2007 Jun; 24(6). Journal Article

Wang Q, Morris ME; The role of monocarboxylate transporter 2 and 4 in the transport of gamma-hydroxybutyric acid in mammalian cells. Drug Metab Dispos; 2007 May; 35(8). Journal Article

Moon YJ, Zhang S, Brazeau DA, Morris ME; Effects of the flavonoid biochanin A on gene expression in primary human hepatocytes and human intestinal cells. Mol Nutr Food Res; 2007 Mar; 51(3). Journal Article

Wang X, Morris ME; Effects of the flavonoid chrysin on nitrofurantoin pharmacokinetics in rats: potential involvement of ABCG2. Drug Metab Dispos; 2007 Feb; 35(2). Journal Article

Wang Q, Morris ME; Flavonoids modulate monocarboxylate transporter-1-mediated transport of gamma-hydroxybutyrate in vitro and in vivo. Drug Metab Dispos; 2007 Feb; 35(2). Journal Article

Moon YJ, Brazeau DA, Morris ME; Effects of flavonoids genistein and biochanin a on gene expression and their metabolism in human mammary cells. Nutr Cancer; 2007 Jan; 57(1). Journal Article

Wang Q, Lu Y, Yuan M, Darling IM, Repasky EA, Morris ME; Characterization of monocarboxylate transport in human kidney HK-2 cells. Mol Pharm; 2006 Nov; 3(6). Comparative Study

Morris ME; Flavonoid-drug interactions: effects of flavonoids on ABC transporters. Proceedings of the 11th Shizuoka Forum on Health and Longevity; 2006 Oct.

Wang Q, Darling IM, Morris ME; Transport of gamma-hydroxybutyrate in rat kidney membrane vesicles: Role of monocarboxylate transporters. J Pharmacol Exp Ther; 2006 Aug; 318(2). In Vitro

Moon YJ, Sagawa K, Frederick K, Zhang S, Morris ME; Pharmacokinetics and bioavailability of the isoflavone biochanin A in rats. AAPS J; 2006 Jul; 8(3). Journal Article

Dr. Jun Qu

Drake EJ, Cao J, Qu J, Shah MB, Straubinger RM, Gulick AM; The 1.8 A crystal structure of PA2412, an MbtH-like protein from the pyoverdine cluster of Pseudomonas aeruginosa. J Biol Chem; 2007 Jul; 282(28). Journal Article

Qu J, Qu Y, Straubinger RM; Ultra-sensitive quantification of corticosteroids in plasma samples using selective solid-phase extraction and reversed-phase capillary high-performance liquid chromatography/tandem mass spectrometry. Anal Chem; 2007 May; 79(10). Journal Article

Straubinger RM, Krzyzanski W, Francoforte CM, Qu J; Applications of quantitative pharmacodynamic effect markers in drug target identification and therapy development. Anticancer Res; 2007 May; 27(3A). Journal Article

Straubinger RM, Qu J; Proteomic approaches to the quantification of pharmacodynamic effect markers: General applications in drug target and biomarker identification ANTICANCER RESEARCH; 2007 May; 27(3A).

Dr. Murali Ramanathan

Chanda P, Zhang A, Brazeau D, Sucheston L, Freudenheim JL, Ambrosone C, Ramanathan M, Brazeau DA; Information-theoretic metrics for visualizing gene-environment interactions. Am J Hum Genet; 2007 Nov; 81(5). Journal Article

Garg N, Weinstock-Guttman B, Bhasi K, Locke J, Ramanathan M; An association between autoreactive antibodies and anti-interferon-beta antibodies in multiple sclerosis. Mult Scler; 2007 Aug; 13(7). Journal Article

Garg N, Zivadinov R, Ramanathan M, Vasiliu I, Locke J, Watts K, Lema J, Rajeswary J, Munschauer FE, Ambrus J, Weinstock-Guttman B; Clinical and MRI correlates of autoreactive antibodies in multiple sclerosis patients. J Neuroimmunol; 2007 Jul; 187(1-2). Journal Article

Weinstock-Guttman B, Tama�o-Blanco M, Bhasi K, Zivadinov R, Ramanathan M; Pharmacogenetics of MXA SNPs in interferon-beta treated multiple sclerosis patients. J Neuroimmunol; 2007 Jan; 182(1-2). Journal Article

Hwang W, Cho YR, Zhang A, Ramanathan M; A novel functional module detection algorithm for protein-protein interaction networks. Algorithms Mol Biol; 2006 Dec; 1. Journal Article

Chadha K, Weinstock-Guttman B, Zivadinov R, Bhasi K, Muhitch J, Feichter J, Tama�o-Blanco M, Abdelrahman N, Ambrus J, Munschauer F, Ramanathan M; Interferon inhibitory activity in patients with multiple sclerosis. Arch Neurol; 2006 Nov; 63(11). Comparative Study

Weinstock-Guttman B, Hong J, Santos R, Tama�o-Blanco M, Badgett D, Patrick K, Baier M, Feichter J, Gallagher E, Garg N, Ramanathan M; Interferon-beta modulates bone-associated cytokines and osteoclast precursor activity in multiple sclerosis patients. Mult Scler; 2006 Oct; 12(5). Comparative Study

Bhasi K, Zhang L, Brazeau D, Zhang A, Ramanathan M; Information-theoretic identification of predictive SNPs and supervised visualization of genome-wide association studies. Nucleic Acids Res; 2006 Aug; 34(14). Evaluation Studies

Hwang W, Cho Y, Zhang A, and Murali Ramanathan; Signal transduction model based functional module detection algorithm for protein-protein interaction networks ; 2006 Aug. Abstract

Cho Y, Hwang W, Zhang A and Murali Ramanathan; Assessing hierarchical modularity in protein interaction networks ; 2006 Aug. Abstract

Dr. Jerome Schentag

Noskin GA, Rubin RJ, Schentag JJ, Kluytmans J, Hedblom EC, Jacobson C, Smulders M, Gemmen E, Bharmal M; National trends in Staphylococcus aureus infection rates: impact on economic burden and mortality over a 6-year period (1998-2003). Clin Infect Dis; 2007 Nov; 45(9). Journal Article

Iannini PB, Paladino JA, Lavin B, Singer ME, Schentag JJ; A case series of macrolide treatment failures in community acquired pneumonia. J Chemother; 2007 Oct; 19(5). Journal Article

Kiem S, Schentag JJ; Interpretation of antibiotic concentration ratios measured in epithelial lining fluid. Antimicrob Agents Chemother; 2007 Sep. Journal Article

Schentag JJ, Klugman KP, Yu VL, Adelman MH, Wilton GJ, Chiou CC, Patel M, Lavin B, Paladino JA; Streptococcus pneumoniae bacteraemia: pharmacodynamic correlations with outcome and macrolide resistance--a controlled study. Int J Antimicrob Agents; 2007 Sep; 30(3). Journal Article

Paladino JA, Sunderlin JL, Adelman MH, Singer ME, Schentag JJ; Observations on vancomycin use in U.S. hospitals. Am J Health Syst Pharm; 2007 Aug; 64(15). Journal Article

Moise PA, Sakoulas G, Forrest A, Schentag JJ; Vancomycin in vitro bactericidal activity and its relationship to efficacy in clearance of methicillin-resistant Staphylococcus aureus bacteremia. Antimicrob Agents Chemother; 2007 Jul; 51(7). In Vitro

Schentag JJ, Hill G, Chu T, Rayner CR; Similarity in pharmacokinetics of oseltamivir and oseltamivir carboxylate in Japanese and Caucasian subjects. J Clin Pharmacol; 2007 Jun; 47(6). Comparative Study

Paladino JA, Eubanks DA, Adelman MH, Schentag JJ; Once-daily cefepime versus ceftriaxone for nursing home-acquired pneumonia. J Am Geriatr Soc; 2007 May; 55(5). Comparative Study

Paladino JA, Adelman MH, Schentag JJ, Iannini PB; Direct costs in patients hospitalised with community-acquired pneumonia after non-response to outpatient treatment with macrolide antibacterials in the US. Pharmacoeconomics; 2007 Jan; 25(8). Journal Article

LeBlanc JM, Dasta JF, Pruchnicki MC, Schentag JJ; Impact of disease states on the pharmacokinetics and pharmacodynamics of angiotensin-converting enzyme inhibitors. J Clin Pharmacol; 2006 Sep; 46(9). Journal Article

Mr. David Soda

No Recent Publications

Dr. Robert Straubinger

Ramani K, Miclea RD, Purohit VS, Mager DE, Straubinger RM, Balu-Iyer SV; Phosphatidylserine containing liposomes reduce immunogenicity of recombinant human factor VIII (rFVIII) in a murine model of hemophilia A. J Pharm Sci; 2007 Aug. Journal Article

Drake EJ, Cao J, Qu J, Shah MB, Straubinger RM, Gulick AM; The 1.8 A crystal structure of PA2412, an MbtH-like protein from the pyoverdine cluster of Pseudomonas aeruginosa. J Biol Chem; 2007 Jul; 282(28). Journal Article

Qu J, Qu Y, Straubinger RM; Ultra-sensitive quantification of corticosteroids in plasma samples using selective solid-phase extraction and reversed-phase capillary high-performance liquid chromatography/tandem mass spectrometry. Anal Chem; 2007 May; 79(10). Journal Article

Straubinger RM, Krzyzanski W, Francoforte CM, Qu J; Applications of quantitative pharmacodynamic effect markers in drug target identification and therapy development. Anticancer Res; 2007 May; 27(3A). Journal Article

Straubinger RM, Qu J; Proteomic approaches to the quantification of pharmacodynamic effect markers: General applications in drug target and biomarker identification ANTICANCER RESEARCH; 2007 May; 27(3A).

K Ramani, RD Miclea, P Gaitonde, RM Straubinger, SV Balu-Iyer; Passive Transfer of Polyethyleneglycol to Liposomal-Recombinant Human FVIII Enhances its Efficacy in a Murine Model for Hemophilia A Journal of Pharmaceutical Sciences; 2007 Jan.

Dr. Kenneth Tramposch

No Recent Publications

Dr, David Triggle

No Recent Publications

Dr. Aiming Yu

Felmlee MA, Lon HK, Gonzalez FJ, Yu AM; Cytochrome P450 expression and regulation in CYP3A4/CYP2D6 double transgenic humanized mice. Drug Metab Dispos; 2007 Nov. Journal Article

Yu AM; Small interfering RNA in drug metabolism and transport. Curr Drug Metab; 2007 Oct; 8(7). Journal Article

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Pharmaceutical Sciences Faculty PublicationsWithin the Past 2 Years

Pharmaceutical Sciences Faculty Publications
Within the Past 2 Years